The energetic, always cheerful lead has pretty good odds of making it out alive in the finale. If we look at other, similar shows like 'The Office' or '30 Rock', both Michael Scott and Liz Lemon weren't killed off in the last episode, which makes it likely for Leslie to survive as well. However, they might try and surprise us by having her get run over by a bus in the last scene. Maybe a bus with her presidential campaign sign on it?
Ron is a pretty tough guy. Even the most horrible disaster will probably not affect him, as he is likely to be prepared for anything that may come. Ron is also a very beloved character, and his death might upset many viewers, so it is unlikely that he will be terminated. If he were to die in the finale, my guess is it will be a "Faking your own death" situation, with the last scene showing Ron escaping the town at night, carrying all his gold and starting a new life somewhere.
Aziz Ansari's character is very unpredictable. He's reckless and a bit self absorbed, which might make him a target. But killing him off might send the wrong message about the show. The writers will probably want to avoid having the last episode bring on a discussion about race in Television, which is why Tom will probably make it out happy and alive.
The goofball couple have seen their share of dangers throughout the show, and survived. Andy is always getting hurt and getting better, especially with his new 'Guardians of the Galaxy' abs. And April is so obsessed with death that killing her off might actually be unsurprising to viewers. My guess is these two will be okay in the end.
Ben joined the series after two seasons, which could mean he will be murdered in the end. But since he is married to Leslie, he gets immunity. We love Leslie and would hate to see her sad, and have her triplets grow up fatherless. Its really not the sort of theme the show is known for. Also, Ben loves Game of Thrones, which has too much death in it already. So Ben lives!
Okay, come on people. Don't you see a pattern here? It's a sitcom, no one is going to be killed off. This isn't American Horror Story or Two and a Half Men. It's a cheery, happy comedy on a major network. Your television bloodlust has crossed a line. If you don't stop tweeting your shocked reviews or posting your friends reaction videos on Youtube, every TV executive will think the only way to get some buzz on a show is by killing people left and right. Pretty soon all TV will just be one murder scene after another. Stop being so cruel. You're supposed to love these characters, not wish for their decapitation.
Okay, I admit. It'll actually be pretty funny if Jerry dies.